The time period in which you have to sue for a claim is known as the "statute of limitations". These statutes not only vary by state, but they also vary by cause of action.
A personal injury action must be filed within 2 years of the date when the injury occurred; this includes medical malpractice and personal injury claims. Pennsylvania does, however, have a "discovery rule," which, in limited cases, extends the time for filing a personal injury action. Under this rule, the statute of limitations will begin to run at the time the plaintiff knows, or should have known, that he or she was injured and that the injury was caused by another's conduct.
Note: Except in cases of wrongful death, an "unemancipated minor" must file suit within two years of his or her 18th birthday.